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Polyglandular Deficiency Syndromes

Overview :

the endocrine system is a diverse group of glands located all over the body that work together to regulate the body's metabolic activities. It includes:

  • the pituitary gland, located deep in the brain, is considered the master gland that regulates many of the others
  • the thyroid gland is located in the neck and sets the metabolic speed of many processes,
  • the parathyroid glands, attached to the back of the thyroid, regulate calcium balance,
  • the adrenal glands are located on top of the kidneys and make four separate kinds of hormones,
  • the gonads (sex organs) produce sex hormones,
  • the pancreas is responsible for the production of digestive juices, insulin, and glucagon.

There are over a dozen different syndromes that involve failure of more than one endocrine gland.

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